Clinical Test Expectation – Tesofensine – Human Subjects : Decreased body fat. Decrease in body weight and reduction in BMI. Improvements in waist and hip circumference.Decreased visceral fat. Decreased very-low-density lipoprotein & triglycerides. Decreased insulin. Better regulation of glucose metabolism. Potential of reversing early type 2 diabetes
Strength – 5mg
Introduction
Tesofensine is a noradrenaline, dopamine, and serotonin reuptake inhibitor. This means that the medication prevents our synapses from taking these neurotransmitters away. In turn, we’re left with more noradrenaline, dopamine, and serotonin in our system. This mechanism may sound familiar because mental health medications, including eating disorder medications, use a similar process. However, these medications don’t produce the weight loss many patients look for.
Originally, researchers looked at Tesofesine as a potential treatment for Parkinson’s and Alzheimer’s. However, in clinical trials, patients began losing too much weight. The extreme weight loss put the trial on hold. Because of this finding, scientists began analyzing the medication for use in patients looking to lose weight. After shifting their focus toward Tesofensine as a weight loss drug, scientists found that it reduces the patient’s appetite. By stimulating our cholinergic system, tesofensine has become more successful than average weight loss remedies. Our cholinergic systems regulate a variety of systems in our bodies, including sensory processing, attention, sleep, and arousal. So, stimulating this system allows our bodies to work faster than normal.
Additionally, Tesofensine increases the near transmission of monoaminergic neurotransmitters, which regulate energy balance. Each of the neurotransmitters it affects has a connection to obesity and depression. By increasing these neurotransmitters, Tesofesine is reducing the chance of both obesity and depression.
This peptide is a novel triple monoamine reuptake inhibitor that induces weight loss primarily by reducing food intake with a slight effect on energy expenditure
Dosing Details
You inject 2ml water into the vial of Tesofensine from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 40 (40 units) on the syringe at any time of day / night and place under the tongue for 30 seconds every 3rd day.
How long will a vial last ?
A vial should last 5 days.
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